Our research
About the lab →
Single cell sequencing
We can analyze thousands or even millions of cells in a single experiment to ask how cell composition and signaling pathways change in disease
Genetics in single cells
We can measure the effect of germline and somatic variation in single cells to ask how genetic background affects disease progression
Spatial profiling
We can determine the location of injured cell types in the kidney and quantify changes in intercellular signaling
Digital PCR and Somatic Mosaicism
We have developed digital PCR assays to quantify the abundance of chromosomal gains and losses in complex tissues
Latest news
All news →Software release: P3Bind for PDZ–PBM binding affinity prediction
Yongqi Huang released P3Bind, an interaction-aware sequence framework for quantitative PDZ–PBM binding affinity prediction. It supports m...
Wilson lab receives its first NIDDK R01 to study DCLK1 isoform switching in kidney disease
The Wilson lab has been awarded an R01 from the NIDDK, DCLK1 isoform switching and proximal tubule injury in kidney disease (2026–2031). ...
Our 2026 lab photo
The Wilson lab has grown over the past year! Say hello to Roy Chen, Yibo Shi, Huihan Liu and Yongqi Huang, who joined the team. Meet ever...
Recent talks
All talks →Somatic Chromosomal Mosaicism and CKD
ASN Kidney Week 2026
Targeting DCLK1 in polycystic kidney disease
Penn Orphan Disease Center
Somatic copy-number profiles reveal stress-response states at single-cell resolution
Penn Institute for Regenerative Medicine
Join the lab!
We're always looking for talented researchers and collaborators. Send us an email or find us on social media.