Software release: P3Bind for PDZ–PBM binding affinity prediction
Yongqi Huang released P3Bind, an interaction-aware sequence framework for quantitative PDZ–PBM binding affinity prediction. It supports motif preference analysis, specificity-aware PBM peptide design, and natural PBM variant-effect analysis. PDZ interactions are a recurring theme in the lab’s DCLK1 work, and P3Bind helps us design peptides that target these interactions.