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Talk
Tracing Somatic Mosaicism
Kidney Development Day · August 2024

Dr. Wilson presented at Kidney Development Day. The talk showed that LOY is most abundant in the kidney cortex and increases with age, that autosomal copy number alteration burden is highest in fibroblasts and mononuclear cells, and that X chromosome alterations are enriched in injured proximal tubule. He also introduced DEFND-seq for detecting alterations in inaccessible chromatin.