Talk at CRRT Conference: The Discovery Pipeline: Molecules, Mechanisms and Targets — Single Cell Sequencing and Spatial Profiling in AKI
Dr. Wilson presented how single-cell sequencing and spatial profiling can be used to discover molecules, mechanisms and targets in acute kidney injury. Using a repeated low-dose cisplatin model, the lab found chromosome 19 gains in proximal tubule and injury-associated microenvironments where injured proximal tubule, macrophages and fibroblasts co-localize.