Talk at Penn Pathology Grand Rounds: Somatic copy number alteration and pro-oncogenic factors as drivers of non-neoplastic disease

Talk

Somatic copy number alteration and pro-oncogenic factors as drivers of non-neoplastic disease

Penn Pathology Grand Rounds · June 2026

Dr. Wilson presented Grand Rounds in the Penn Department of Pathology and Laboratory Medicine. A key finding was that the somatic copy number profile of injured proximal tubule resembles renal cell carcinoma, which suggests that pro-oncogenic alterations and factors such as DCLK1 may drive non-neoplastic kidney disease.