Talk at Penn PLM Research Day 2025: Senescence and DNA damage in kidney disease progression

October 3, 2025 less than 1 minute read

Talk

Senescence and DNA damage in kidney disease progression

Penn PLM Research Day 2025 · October 2025

Dr. Wilson presented at the Penn Pathology and Laboratory Medicine Research Day. Injured proximal tubule cells are found in healthy kidney and increase with aging and CKD. They carry more somatic copy number alterations, are the most likely to have lost the Y chromosome, and express the oncogene DCLK1, a candidate therapeutic target.

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Talk at ASN Kidney Week 2026: Somatic Chromosomal Mosaicism and CKD

October 22, 2026 less than 1 minute read

Dr. Wilson spoke at ASN Kidney Week 2026 about somatic chromosomal mosaicism in chronic kidney disease. He described how CHASM detects copy number alteration...

Talk at Penn Orphan Disease Center: Targeting DCLK1 in polycystic kidney disease

October 15, 2026 less than 1 minute read

Dr. Wilson presented at the Penn Orphan Disease Center on targeting DCLK1 in polycystic kidney disease. Single-cell sequencing found increased DCLK1 in injur...

Software release: P3Bind for PDZ–PBM binding affinity prediction

October 7, 2026 less than 1 minute read

Yongqi Huang released P3Bind, an interaction-aware sequence framework for quantitative PDZ–PBM binding affinity prediction. It supports motif preference anal...

Talk at Penn Institute for Regenerative Medicine: Somatic copy-number profiles reveal stress-response states at single-cell resolution