Talk at Joslin Diabetes Center: Single-cell and spatial omics in kidney disease progression
Dr. Wilson was invited to speak in the Joslin Diabetes and Metabolism Research Lecture Series. He described how injured proximal tubule cells accumulate somatic copy number alterations that change expression of the affected chromosomes, and how DCLK1, which is associated with diabetic kidney disease by genome-wide meta-analysis, is expressed in these cells.